Post-doctoral positions available for Alzheimer’s disease research

Post-doctoral positions available for Alzheimer’s disease research

Two post-doctoral positions are available to work in the Laboratory for Neurodegenerative Disorders, Institute of Medical Biochemistry, Federal University of Rio de Janeiro (Brazil), under the joint supervision of Profs. Sergio T. Ferreira and Fernanda G. De Felice. Current positions are funded by fellowships from the Brazilian National Research Council (CNPq/PNPD) and by the Foundation for Research Support of the State of Rio de Janeiro (FAPERJ/PAPD), and are initially for a one-year period (renewable depending on project development and performance evaluation). Both positions are linked to an on-going research program on the molecular, cellular and systemic mechanisms of pathogenesis of Alzheimer’s disease (AD).

One of the open positions is to work in a project aiming to develop novel viral vectors for delivering anti-A antibodies to the brain in experimental models of AD. Development of the viral vectors is already under way with external collaborators, and characterization of safety and efficacy should be initiated in the near future. The ultimate goal is to develop a safe, efficacious immune approach to prevent neuronal dysfunction and memory impairment in AD.

The second position is to work in a project related to the molecular links between AD, diabetes and depression recently discovered by our group. Several lines of investigation in the lab currently address these issues, and the post-doc fellow will be able to join and/or lead one or more of them.

We are looking for candidates who are highly motivated to pursue a productive career in Science. Successful previous research experience and training in biochemistry, molecular biology, cell biology and behavioral studies (though not necessarily in all of these areas) are strongly desired. Fellowships are available beginning in August 2013, and applications (CV plus letter describing previous training/research experience and current research interests to be sent by email to will be received until positions are filled. Successful applicants will join a vibrant research team working with adequate funding and laboratory infrastructure for development of the proposed projects.

Selected recent publications: Bomfim et al. (2012) J. Clin. Invest. 122:1339-1353; Sebollela et al. (2012) J. Biol. Chem. 287:7436-7445; Ledo et al. (2012) Mol. Psychiatry 2012 Nov 27. doi: 10.1038/mp.2012.168. [Epub ahead of print]; Figueiredo et al. (2013) J Neurosci. 2013 Jun 5;33(23):9626-34. doi: 10.1523/JNEUROSCI.0482-13.2013.

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